Current Research: 'Heart Disease Starts in Childhood'
A 1953 study published in JAMA documented coronary disease among United States soldiers killed in action in Korea. In a series of 300 autopsies performed on United States battle casualties in Korea, the average age of 22 years, 77% of the hearts had some gross evidence of coronary arterial sclerosis! Some of them had vessels that were clogged 90% or more. This study dramatically showed that atherosclerotic changes appear in the coronary arteries years and decades before the age at which coronary heart disease (CHD) becomes a clinically recognized problem. Follow-up studies from over 1500 coronary arteries acquired from autopsy material from 1954 1960 confirmed the original results.
How young does it go? Atherosclerosis begins in childhood with the appearance of aortic fatty streaks, the first stage of atherosclerosis. Aortic fatty streaks of some degree are present in practically all individuals from every human population that has been studied. In a 1969 study fatty streaks were found in 100% of kids by age 10!
What is accounting for this build up of plaque in the arteries of young children? In the 1980s we got our first clue from the famous Bogalusa Heart Study that looked at autopsies of those dying between the ages of three and 26 years. The number one risk factor was cholesterol. You could see the stepwise increase in the amount of their arteries covered by fatty streaks as the level of bad cholesterol in the blood increased. But this study only looked at 30 subjects. So, they decided to study 3,000 youth and atherosclerosis. 3000 accidental death victims ages 15 to 34 years old were evaluated. After developing a risk factor scoring system it was determined that a non-HDL cholesterol over to 120 mg/dL was a powerful risk factor for coronary artery disease. It was determined that a 16-year-old female with an elevated risk score can expect to have serious heart disease by age 30 without a modification in diet. Even in 15 to 19-year-olds, atherosclerosis has begun in a substantial number of individuals, and this observation suggests beginning primary prevention at least by the late teenage years to ameliorate every stage of atherosclerosis and to prevent or retard progression to more advanced lesions. You start kids out on a low saturated fat diet and you can see a significant improvement in their arterial/endothelial function by 11 years old. Exposure to high serum cholesterol concentration in childhood may accelerate the development of atherosclerosis, even in childhood. Consequently, the long-term prevention of atherosclerosis will be most effective when initiated early in life, e.g. by seven months of age!
Atherosclerosis, hardening of the arteries, begins in childhood and progresses during adolescence and young adulthood; by age 10 nearly all kids have fatty streaks, the first stage of the disease. Then, the plaque starts forming in the 20s, and progresses from there; by the 40s people start dying. In our hearts, it is a heart attack; in our brain, is a stroke; in our extremities it can mean gangrene; in our aorta, it can mean an aneurysm. So, by age 10 the question is whether you want to reverse the heart disease you already have. Doctors Ornish and Esselstyn proved that you can reverse heart disease with a plant based diet.; So, we can start reversing heart disease in our children tonight! wz